Tree in Bud Sign The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular nodules. It is caused by opacified bronchioles surrounded by centrilobular nodules. Initially described in endobronchial TB, it is actually seen in all causes of infective bronchiolitis ljke bacterial/viral/fungal pneumonia, congenital causes like cystic fibrosis, connective tissue disorders and even neoplastic conditions like bronchioalveolar cell carcinoma. Dr. Devpriyo Pal @drdevrad #Tree #Bud #TreeInBud #Sign #diagnosis #clinical #radiology #ChestCT #pathophysiology
