Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA - SLE
Anti-histone - Drug-induced SLE
Anti-Jo-1 - Polymyositis / Dermatomyositis
Anti-LKM (liver kidney microsomal) - Autoimmune hepatitis
Anti-mitochondrial (AMA), Anti-sp100, Anti-gp210 - Primary biliary cirrhosis (PBC)
Anticentromere - CREST syndrome
Anti-Scl-70 - Scleroderma (Diffuse)
Anti-Sm - SLE
Anti-SSA (Ro), Anti-SSB (La) - Sjogren's syndrome
Anti-TSHR - Graves' disease
c-ANCA - Vasculitis, e.g. Wegener's granulomatosis
p-ANCA - Vasculitis, e.g. Microscopic polyangiitis
U1-RNP antibody - Mixed connective tissue disease
Endomyseal antibody (EMA), Tissue transglutaminase (TTG) - Celiac disease
Anti-GBM - Goodpasture's syndrome
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