Alpha-gal Syndrome (AGS) - Diagnosis Algorithm Does patient have recurrent episodes of urticaria, angioedema or isolated GI distress? Pertinent History for AGS (If patient affirms ≥2 of these boxes, then consider testing for alpha-gal IgE): • Timing - Nighttime symptoms are most common - Itching - often an early symptom • Ticks - Known tick bites and/or a history of outdoor activities in areas with ticks - Persistent irritation at site of tick bite • Diet - Beef, pork, Iamb, venison in diet - High fat dairy in diet #AlphaGal #Syndrome #AGS #Diagnosis #Algorithm #allergy