Diagnostic Scoring System for Wilson's Disease - Kayser-Fleischer rings (2 points) - Neurological symptoms (2 points) - Serum ceruloplasmin (2 points) - Coombs-negative hemolytic anemia (1 point) - Liver copper (in the absence of cholestasis) (2 points) - Urinary copper (in the absence of acute hepatitis) (2 points) - Mutation analysis (4 points) Evaluation: Total Score ≥ 4 - Diagnosis established Total Score 3 - Diagnosis possible; more tests needed Total Score ≤ 2 - Diagnosis very unlikely #Wilsons #Disease #Scoring #diagnosis #neurology
