Alcohol Use Disorder - Maintenance Treatment Naltrexone (first line) - First line for most people without contraindications - Dosing: 50 mg PO qday OR 380 mg IM qmonth Topiramate - Consider if also using cocaine, PTSD, seizure hx, overweight - Dosing: Goal 150 mg BID (slowly uptitrate) Baclofen - Consider if also chronic pain, liver disease - Dosing: 10-20 mg TID Gabapentin - Consider if neuropathic pain, anxious, EtOH withdrawal. Helps when added to naltrexone if naltrexone had some efficacy - Dosing: 600 mg TID Acamprosate (FDA approved) - Patients who are already abstaining, prevents relapse, safe in liver disease - Dosing: 2x 333 mg tablets TID Disulfiram (FDA approved) - Patients who are already abstaining, prevents relapse, only effective if observed dosing by family, opioid treatment program - Dosing: 250-500 mg qday Varenicline - Men who are also smokers - Dosing: 2mg qday (start with 0.5 qday and uptitrate) #AUD #Alcohol #Use #Disorder #Maintenance #Treatment #management #pharmacology #table #addiction
