What interventions do have proven mortality benefit? The above factors predict that it's nearly impossible to prove mortality benefit in critical care. What does the literature show? The great majority of RCTs with a mortality endpoint are negative. Ospina-Tascon 2008, Ridgeon 2016, and Landoni 2015 sifted through decades of critical care literature looking for multicenter RCTs showing a mortality benefit. Based on these studies, below is a list of medications with mortality benefit (1) #EBM #CriticalCare #Medications #MortalityBenefit #Table #RCT #PulmCrit
