Syphilis Serologic Testing - Treponemal and Non-Treponemal Testing Algorithms Treponemal Testing: • Confirmatory or Screening - Detection of antibodies directed against specific treponemal antigens. • Specific = Definitive • High Cost • FTA-ABS, MHA-TP, TPPA, TP-EIA, CIA Non-Treponemal Testing: • Reactivity of patient serum to a cardiolipin-cholesterol-lecithin antigen. • Nonspecific = Not Definitive • Low Cost, Fast • RPR, VDRL, TRUST By @TheIDtrivia #Syphilis #Serologic #Testing #diagnosis #Treponemal #NonTreponemal #microbiology #infectiousdiseases
