Tularemia - Diagnosis and Management Summary Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection • Ulceroglandular: Fever + erythematous papulo-ulcerative lesion; Tender lymphadenopathy; +/- suppuration • Glandular: Regional lymphadenopathy single or multiple nodes (suppurative); Most common presentation among children; No evident lesion at the site of inoculation • Oculoglandular: Splashing infected material into eye; unilateral symptoms (pain, photophobia, increased tearing); Parinaud's Oculoglandular Sx • Pharyngeal: Ingestion of contaminated food/water; small percentage in the United States • Pneumonic: Direct inoculation of the organism into the lungs; More common in adults - farmers, sheep shearers, landscapers • Typhoidal: Systemic febrile illness without prominent regional adenopathy; Affected patients often have chronic underlying conditions Diagnosis: Serology (preferred), Culture & GS, PCR Treatment: • Severe Disease: Gentamicin, Streptomycin • Moderate Disease: 1) Ciprofloxacin / Levofloxacin 2) Doxycycline By @TheIDtrivia #Tularemia #Francisella #tularensis #diagnosis #management #treatment #infectiousdiseases #microbiology
