Cardiorenal Syndrome (CRS) Types
• Type 1 - Acute CRS: Alteration of renal perfusion is the main trigger (in particular when congestive heart failure is present)
• Type 2 - Chronic CRS: Renal fibrosis is particularly important in type 2. Also to be considered drug induced renal toxicity and VAD induced renal effects
• Type 3 - Acute RCS: Salt and water, neuro-hormonal and uremia induced dysregulations are the most important aspects
• Type 4 - Chronic RCS: Hypertension, CKD induced myopathy, chronic hemodialysis and fluids shifts may be in cause
• Type 5 - Secondary CRS: Common pathogenetic patterns (i.e. auto-immunity, micro-circulatory dysfunction, cytokine release)
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