Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 - End-organ malperfusion - Lactate > 1.5 High CO / Low SVR: • Distributive: Sepsis, Anaphylaxis, Adrenal Insufficiency, Liver Failure, Toxins/Medications, Spinal Cord Injury Low CO / High SVR: • Cardiogenic: Myocardial Infarction, Decompensated CHF, Severe Valve Disease, Myocarditis, Arrhythmia • Obstructive: Pulmonary Embolism, Tension Pneumothorax, Cardiac Tamponade, Severe pHTN, Constrictive pericarditis, Severe auto-PEEP, Abdominal compartment syndrome, Vascular compression • Hypovolemic: Blood Loss, GI Losses, Third Spacing, Extreme Dehydration Shock Treatment Goals: 1) MAP > 60-65 2) Lactate < 2.0 3) UOP > 0.5 cc/kg/hr Sophia Hayes MD @Sophia_Hayes_MD #Shock #Differential #Diagnosis #criticalcare #algorithm #treatment #management