Severe Asthma Exacerbation Signs of a Severe Asthma Exacerbation: • Vitals: ↑HR ↑RR ↓SpO2 • High work of breathing / accessory muscle use • Inability to speak in full sentences • Diffuse wheezing OR poor air flow • ABG: - High pCO2 / low pH - Abnormally normal ABG with increased work of breathing • Peak flow - < 200 L/ min or - ≤ 50% of baseline Treatments for Severe Asthma: • Nebulized Bronchodilators: Albuterol, Ipratropium • Adjunctive therapies: IV Mg, Heliox, Ketamine, IV beta agonists • Glucocorticoids: Methylprednisolone, Prednisone • NIPPV: BiPAP, Brief trial Mechanical Ventilation in Asthma: • Volume control mode of ventilation • Initial ventilator settings • Manage Ventilator Dyssynchrony • Monitor for Improvement By @PulmPEEPs #Asthma #Exacerbation #CriticalCare #pulmonary #ventilation #mechanical #management #treatment