Approach to Gout Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals Treatment: • Weight loss, diet, d/c culprit medications • Acute: NSAIDs, Steroids, Anakinra • Colchicine: Acute and chronic treatment • Chronic - Urate Lowering Therapy: Xanthine Oxidase Inhibitors (Allopurinol, Febuxostat), Pegloticase When to start Urate Lowering Therapy (ULT): 1) 2+ flares/year 2) Gouty tophi 3) Radiographic Damage 4) Urate nephropathy, renal stones Dr. Kristen Carroll @NUIM_Chiefs #gout #diagnosis #management #treatment #ULT #rheumatology
