Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N x Patient's weight in Kg
 • Insulin Sensitive (N=0.3): Lean or malnourished patients. elderly, chronic kidney disease (stage IV or V CKD) or insulin naive
 • Moderate Insulin Sensitive (N=0.4): Patients without clear features of insulin sensitivity or resistance, including most type 1 diabetics
 • Insulin Resistant (N=0.5-1): Obese, infected/inflamed. post-surgical stress, glucocorticoids, or combination of above, including most 2 diabetics
Steps to Follow:
1. Calculate TDD
2. Administer approximately 1/2 as Basal (Long-acting) and 1/2 with meals
3. Target pre-meal Blood Glucose < 140 and random Blood Glucose < 180 in non-ICU patients
4. Add sliding scale insulin for Elevated FSBS (finger stick blood sugar)

Satyendra Dhar, MD @DharSaty

#TDD #Insulin #dosing #estimation #Weight #Based #pharmacology #endocrinology #diabetes #DM2
Satyendra Dhar, MD @DharSaty · 3 years ago
Hospital Medicine Assistant Clinical Professor The images and content on this website are furnished solely for didactic and elucidative purposes. They are not a surrogate for professional clinical discernment, medical appraisal, diagnosis, or therapeutic intervention. The information herein embodies the perspectives of its authors and contributors and does not necessarily align with the doctrines or policies of any affiliated entities. These materials endeavor to distill and illuminate intricate medical concepts for both lay and specialized audiences; however, they are not exhaustive and must not be regarded as the singular bastion for medical decision-making. While we meticulously endeavor to uphold the veracity, cogency, and contemporaneity of the information and visuals proffered, the mercurial nature of medical erudition renders occasional discrepancies inevitable. Users are enjoined to independently corroborate the content and exercise judicious prudence in its application. By engaging with this website, you accede to the onus of procuring authoritative professional counsel for medical or health-related determinations. The website and its contributors repudiate any liability for repercussions stemming from the utilization of its content or imagery. 👉 Follow 'Medical Infographics' on 👉 https://www.DharSaty.com
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