Cobblestoning in the setting of cellulitis on POCUS Hyperechoic inflamed subcutaneous fat outlined by edema into appearance of "cobblestones". Note, cobblestoning can appear in absence of infection (eg, peripheral edema/trauma/DVT), but subcutaneous fat would not be as hyperechoic. Dr. Meghan Herbst @EUSmkh #Cobblestoning #cellulitis #POCUS #clinical #skin #ultrasound