Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection in any body fluid or tissue specimen regardless of symptoms or signs. Diagnosis: Quantitative PCR and CMV pp65 antigenemia test. For tissue-invasive CMV CMV, inclusions or positive specific immunohistochemistry on histopathology. Suspect these CMV-related conditions in any patient with HIV and CD4 50 or less: • Neurologic: Encephalitis, Myelitis, Polyradiculopathy, Peripheral Neuropathy • Eye: Retinitis (Most common cause of blindness in AIDS) • Liver: Hepatitis, Portal vein thrombosis • Endocrine: Infectious Adrenalitis, Pancreatitis • Pulmonary: Pneumonitis (In association with PJP/TB) • Cardiovascular: Myocarditis, ↑Cardiovascular risk, DVT • Gastrointestinal: Esophagitis, Enteritis, Colitis By @TheIDtrivia #Cytomegalovirus #CMV #HIV #AIDS #diagnosis #differential #signs #symptoms
