(1,3)-β-d-glucan Abundant cell wall polysaccharide, found in most fungi, except cryptococci, zygomycetes (mucor, rhizophus) and blastomyces. Sensitivity 64%-93%; Specificity 87%-100% False Negatives: • Hyperlipemic sample • Hemolyzed blood • Certain fungus that lack (1 ,3)-ß-d-glucan False Positives: • Bacteremia (Streptococcus spp) • Hemodialysis • IVIG • β-Lactams (Pip/Tazo, Amox) • Medications containing lentinan, schizophyllan, scleroglucan. By @TheIDtrivia #beta #dglucan #glucan #betad #fungal #diagnosis #laboratory #microbiology #infectiousdiseases
