Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin B, t-PA, heparin Acute Phosphate Load: • Exogenous: Excessive phosphate intake, Phosphate laxatives, Vitamin D toxicity, Fosphenytoin • Endogenous: Rhabdomyolysis, Tumor lysis syndrome, Hemolysis Transcellular Shift: • Lactic acidosis, DKA Kidney Disease: • AKI, CKD Increased Renal Phosphate Absorption: • Hypoparathyroidism, Acromegaly, FGFR inhibitors, Familial tumoral calcinosis, Bisphosphonates Dr. Aisha Shaikh @aishaikh #Hyperphosphatemia #Differential #Diagnosis #Framework #Workup #phosphate #nephrology
