Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production, & cell function.
 • Contributes to increased HTN, atherosclerotic CVS disease & osteoporosis.
 • Predisposing factor for the development of alcohol-induced pathologies such as cardiomyopathy, sarcopenia, CVA & cirrhosis.
 • Depressive symptoms among alcoholics, especially during the withdrawal period can be attributed to Mg deficiency where Mg regulates the calcium ion stream towards the neuronal calcium channels.
 • Mg deficiency is shown to increased platelet aggregation that was normalized with Mg therapy & this antiplatelet effect may be related to the finding that Mg inhibits the synthesis of thromboxane A2 and 12-hydroxyeicosatetraenoic acid, & eicosanoids.

Satyendra Dhar, MD @DharSaty

#Magnesium #Deficiency #Alcoholism #alcohol #pathophysiology #hypomagnesemia
Satyendra Dhar, MD @DharSaty · 2 years ago
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