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Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies • Stepwise Approach: ACE, ARB, ARNI → Beta-Blocker → MRA → SGLT-2 Inhibitor • Rapid low-dose approach: Beta-Blocker + SGLT-2 Inhibitor → ARNI →MRA CORE IM @COREIMpodcast https://www.coreimpodcast.com/2022/ #Heart #Failure #CHF #HFrEF #Guideline #management #GDMT #cardiology #titration #initiation