Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History of recent symptomatic genital infection is uncommon. Laboratory Diagnosis: • 2 sets of blood cultures should be obtained, along with antimicrobial susceptibility testing • (NAAT) Urethra, pharynx or rectum is the preferred test • Synovial fluid analysis in all patients with suspected DGl who have an accessible joint effusion • Laboratory testing of skin lesion samples is not typically part of the workup • Test all patients for HIV, Chlamydia and Syphilis Arthritis-Dermatitis syndrome: • Fever, chills, generalized malaise • Polyarthralgia • Tenosynovitis • Dermatitis (Painless) Purulent Arthritis Syndrome: • Most patients are afebrile • Acute mono- or oligoarthritis • Distal joints, knees, wrists, ankles • Axial involvement is rare By @TheIDtrivia #Disseminated #Gonococcal #Infection #gonorrhea #Diagnosis #Management #Microbiology #InfectiousDiseases