Satyendra Dhar, MD @DharSaty · 4 years ago
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Lactic acid was first found & described in sour milk by Karl Wilhelm Scheele in 1780.
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Lactic acid was first found & described in sour milk by Karl Wilhelm Scheele in 1780. German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 & 1851. 

Lactic acid is essentially a carbohydrate within cellular metabolism and its levels rise with increased metabolism during exercise and with catecholamine stimulation. Glucose-6-phosphate is converted anaerobically to pyruvate via the Embden-Meyerhof pathway. Pyruvate is in equilibrium with lactate with a ratio of about 25 lactate to 1 pyruvate molecules. Thus, lactate is the normal endpoint of the anaerobic breakdown of glucose in the tissues.


Satyendra Dhar MD, @DharSaty

#Lacticacid, #Lactate, #Shock,
Satyendra Dhar, MD @DharSaty · 4 years ago
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