Periodic Alternating Gaze (PAG) on Physical Exam

Periodic Alternating Gaze (PAG) is an involuntary continuous cyclic horizontal sustained conjugate deviation of the eyes, which alternates sides with a cycle of 1–2 min.
Periodic alternating nystagmus (PAN) is a spontaneous horizontal nystagmus that periodically reverses every 1–2 min, with fast phases alternating between left and right sides, separated by null phases. PAG & PAN are rarely seen together.
However, PAG and PAN share a similar time constant and a common pathological mechanism (instability of the velocity‑storage mechanism [VSM]) of the cerebellum. The VSM is like a wind up clock that stores rotational information beyond the capacity of the semicircular canals and releases it after prolonged rotation.

Dr. Boby Varkey Maramattom @bobvarkey

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Boby Varkey Maramattom @bobvarkey · 2 years ago
Lead consultant Neurologist, Aster Medcity, Kochi, India. Internal medicine faculty Royal college of UK https://twitter.com/bobvarkey
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