Drug-Induced Prolonged QTc QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP) Drugs causing QTc prolongation: • Antiarrhythmics: Amiodarone, Procainamide, Quinidine, Sotalol • Antipsychotics: Chlorpromazine, Clozapine, Haloperidol, Quetiapine, Risperidone • Antibiotics: Azithromycin, Clarithromycin, Erythromycin, Fluconozaole, Ketoconazole, Ciprofloxacin, Levofloxacin, Moxifloxacin, Trimethroprim/Sulfamethoxazole • Antidepressants: Amitriptyline, Citalopram, Fluoxetine, Nortriptyline, Paroxetine, Sertraline, Venlafaxine • Anti-emetics: Ondansetron, Prochlorperazine • Opioids: Methadone • Others: Arsenic trioxide, Cisapride By Dr. Kathryn Watson @Kat_Watson #Drug #Induced #Prolonged #QTc #Toxicity #Toxicology #Pharmacology #Diagnosis #prolongation
