Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD • Class I pillars of HFrEF GDMT across the span of kidney disease: ACEI, ARB, ARNI, BBs, Loop diuretics, MRA, SGLT2i, Nitrate, Vasodilator • Class II "additional therapies" for HFrEF GDMT after core GDMT has been optimized: IKi, sGC stimulator, Chronotropes • Medications that are not strictly defined as part of HFrEF GDMT but are commonly used in HFrEF: Statins, Thiazides By Jiun-Ruey Hu, MD & Jiawei Tan, MD #Guideline #Directed #Medical #Therapy #GDMT #CKD #HFrEF #management #pharmacology #cardiology
