Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a 50% increase in creatinine or absolute increase of 44 mol/L over 24 – 72 hours, with a minimum of 24-72 hours of drug exposure. • Risk of vancomycin induced kidney injury is related to co-morbidities (particularly underlying renal dysfunction), co-prescribing of other nephrotoxic agents, the dose and duration of therapy. • Treatment includes prevention by minimizing risk factors, cessation of therapy, and transitioning to alternative agents By Dr. Kathryn Watson @Kat_Watson #Vancomycin #AKI #pharmacology #toxicology #diagnosis #management #nephrology
