Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive CKD of unclear etiology; oliguria
 • Classic triad (<10%): fever, rash, eosinophilia
 • UA: sterile pyuria, WBC casts, eosinophiluria, microscopic hematuria, mild tubular proteinuria, granular casts/RTE; blend sediment
 • Received drug associated with AIN

Matthew Ho, MD PhD @MatthewHoMD

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