Iron Deficiency in Congestive Heart Failure (CHF) Iron deficiency (ID) in heart failure is a common comorbidity affecting up to 50% of patients, leading to: ↑ HF Hospitalization ↓ Quality of life and hospitalizations survival ↓ Exercise capacity Diagnosis: • Ferritin < 100 ng/mL OR Ferritin 100 - 299 ng/mL + TSAT < 20% Risk Factors: • Female sex • More advanced stages of HF • Higher NT-proBNP and CRP Ganzoni Equation: Iron deficit (mg) = [body weight (kg) x (target Hgb — actual Hgb) x 2.4 + depot iron] Treatment Options (IV Iron Preferred) • Ferric carboxymaltose - 750 mg • Ferric gluconate - 125-150 mg • Ferumoxytol - 510 mg • Iron dextran - 100 mg • Iron sucrose - 100-200 mg By Kyle Fischer, PharmD @Kfischer_10 #Iron #Deficiency #Heart #Failure #CHF #pharmacology #pathophysiology #cardiology
