Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression • Exam: lymphadenopathy, petechiae, splenomegaly, hepatomegaly • Labs: anemia, ↑ MCV, ↑/↓ platelets, persistent WBC > 30k (or > 20k after initial Rx), basophilia, plasmacytosis, monomorphic lymphocytosis, predominant immature cells Matthew Ho, MD PhD @MatthewHoMD #Leukocytosis #Differential #Diagnosis #Algorithm #hematology #WBC #Leukemoid
