Typhlitis - Neutropenic Enterocolitis Pathophysiology: • Chemo → friable intestinal mucosa → bacterial translocation +/- perforation Presentation: • Fever + Abdominal Pain (most often after 3rd week of chemo) • Abdominal distension & dysmotility, N/V/D, hematochezia • Peritonitis (if perforation) • Fever may not abate until ANC recovers! Andrew Sanchez M.D. @ASanchez_PS #Typhlitis #Neutropenic #Enterocolitis #diagnosis #management #oncology #management
