Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ US to look for ductal dilation
3. No dilation = intrahepatic cholestasis - rule out non-ICU vs ICU causes
4. MRCP, ERCP, liver biopsy

Matthew Ho, MD PhD @MatthewHoMD

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