Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 • First-degree relatives with celiac disease
 • Iron-deficiency anemia unresponsive to treatment
 • Elevated liver enzymes without discernable cause
 • Signs of osteoporosis in young individual
 • Individuals with autoimmune thyroiditis, hepatitis, T1DM, Addisons, microscopic colitis

Differential for villous atrophy: 
 • Celiac disease
 • Autoimmune
 • CVID
 • Medications (NSAlDs, ARBs) 
 • Infection (giardia, tropical sprue, whipple) 
 • Inflammatory (IBD, eosinophilic enteritis, collagenous sprue)
 • Lymphoma
 • High acid

Matthew Ho, MD PhD @MatthewHoMD

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