Additional Modalities for Workup of GI Bleed (Other than EGD + Colonoscopy)

Pill endoscopy
 • Able to assess sites beyond push and double-balloon endoscopy limits, high sensitivity for detection of most small-bowel diseases
 • Contraindicated in small-bowel stricture, limited anatomic localization, non-therapeutic, massive bleed may obscure bleeding site
Triple-phase CT Enterography
 • Able to image the mesenteric vasculature in addition to the small bowel mucosa, lumen, and wall, noninvasive
 • Non-therapeutic, contrast allergy or nephropathy
CT angiography
 • Precise localization, noninvasive, rapid and easy to perform
 • Non-therapeutic, contrast allergy or nephropathy 
Mesenteric Angiography
 • Therapeutic
 • Invasive, contrast allergy or nephropathy, unable to perform prolonged imaging
Meckel's Scan
 • Noninvasive
 • False positives can be seen in the presence of small bowel duplication cysts, intussusception, and inflammatory bowel disease
Deep Enteroscopy (e.g., push, double balloon, spiral)
 • Therapeutic, able to tattoo sites for future localization
 • Invasive, technically challenging
Laparoscopy/laparotomy with intraoperative endoscopy
 • Able to assess and intervene on sites beyond push and double-balloon endoscopy limits
 • Invasive, technically challenging
Tagged RBC Scan
 • Most sensitive, noninvasive, ability to image over a prolonged period
 • Poor anatomic localization, unable to identify pathology, non-therapeutic

Matthew Ho, MD PhD @MatthewHoMD

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