Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis (B12 injections in pernicious anemia)
 • G-CSF
 • Hypokalemic periodic paralysis
 • Refeeding syndrome
 • Thyrotoxicosis
Medications
Renal Losses
Non-renal losses: 
 • GI losses (NG suction, diarrhea, vomiting)
 • Low K intake (anorexia, dementia, starvation, TPN)
 • Transcellular shifts
 • Discontinued diuretic

Matthew Ho, MD PhD @MatthewHoMD

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