Digoxin 101 - Pharmacology Indications: 1) Tachyarrhythmias • Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardias • ↑ Vagal tone, ↑ baroreceptor sensitivity leads to AV nodal delay (ie rate control) 2) Heart Failure, reduced EF • If NYHA III or IV symptoms despite GDMT • Na/K Pump Inhibition - ↑ buildup of intracellular calcium leads to more cardiac contractility (ie inotropy) Matt Tsai @thematttsai #Digoxin #Pharmacology #cardiology
