Hemophilia A Prophylaxis (Factor Eight Deficiency) Who Needs Prophylaxis? Primary Prophylaxis: • Severe deficiency (activity level <1%) even without hx of bleeding episodes Secondary Prophylaxis: • 2 bleeding episodes • Mild-to-moderate (Activity 5-40%): consider intermittent ppx • Severe: continuous ppx Tertiary Prophylaxis: • Documented arthropathy • Continuous ppx regardless of severity Dr. Jonathan Berry @jlberrymd #Hemophilia #HemophiliaA #Prophylaxis #FactorEight #Deficiency #hematology #management #ppx
