N-Acetylcysteine (NAC) restores hepatic glutathione! Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure The earlier it is given, the better! Typically used if the serum concentration of acetaminophen falls above the normogram (and some suggest to give if ANY concern for ANY overdose of acetaminophen) #Diagnosis #Toxicology #Nomogram #Acetaminophen #Toxicity #APAP