Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample • Sterile-site biopsy Non-culture-based tests: • Beta-D-Glucan • Molecular Tests Conduct antifungal susceptibility testing (AFST) to guide therapy First Line Targeted Treatment (with AFST) • Echinocandin (strong recommendation) • Lipid amphotericin B • Fluconazole (intravenous or oral) Additional management: • Dilated Funduscopic Exam • CVC Removal • Infectious Diseases Consults • Echocardiogram #Invasive #Candidiasis #IC #antifungal #diagnosis #management #candida #auris #treatment
