Insomnia Medications Natural Products: • Melatonin • Valerian Hypnotics and Antidepressants Non-BZDs: increase GABA • Eszopiclone • Zolpidem Orexin-receptor antagonist: promotes wakefulness • Suvorexant Melatonin Receptor Agonists: induces sleepiness & regulates circadian rhythm • Ramelteon • Tasimelteon Antidepressants: Block H1 receptor & 5-HT effects • Doxepin • Trazodone BZDs & Antihistamines BZDs: Increase GABA • Lorazepam • Temazepam Antihistamines: block H1 blockers • Diphenhydramine • Doxylamine By Kyle Fischer, PharmD @Kfischer_10 #Insomnia #Medications #sleep #pharmacology #treatment #management
