Bacteremia Quick Reference - Treatment Duration
Gram Negative Bacteremia:
• Avoid: Aminoglycosides and tigecycline
• Catheters should be removed in septic shock, suppurative thrombophlebitis, IE, infection due to P. aeruginosa
• ESBL: carbapenems the drug class of choice, some strains be susceptible may to cefepime
• Duration: 7 days preferred, initially IV, consider switching to oral if good bioavailability
• No follow up cultures required
Gram Positive Bacteremia:
• S. aureus and S. lugdunensis - 14 days of IV therapy if meets all of the following criteria:
- Absence of IE
- No indwelling devices
- Follow-up blood cultures are negative.
- No fever within 48 -72 hours after initiating therapy
- No evidence of metastatic infection.
• Streptococcus Pneumoniae 10-14 days therapy. Consider switching to oral if good bioavailability
• Enterococcus 5-7 days therapy (if repeated blood cultures drawn at 24 hours are negative) Use DENOVA score
• Group C and Group G strep - 14 days therapy
By @TheIDtrivia
#Bacteremia #Treatment #Management #Duration #infectiousdiseases
