Diagnosis and Management of Achalasia - ACG Guidelines
Who to suspect?
• Patients presenting with progressive dysphagia to solids and liquids, heart burn, chest pain, regurgitation, and weight loss or nutritional deficiencies.
• Patients diagnosed with GERD who are unresponsiveto acid-suppressive therapy.
What test to order?
• Endoscopy to look for foam or puckering of the EGJ
• Barium esophagogram to look for retained barium or the classic "bird beaking"
• High resolution esophageal manometry (HRM)
Chicago classification for achalasia subtypes
• Achalasia I - aperistalsis+ panesophageal pressurization < 30 mm Hg
• Achalasia II - aperistalsis+ panesophageal pressurization > 30 mm Hg
• Achalasia Ill - spastic contractions
Definitive Treatment:
• Pneumatic Dilation (PD)
• Laparoscopic Heller Myotomy (LHM)
• POEM
Symptomatic Treatment:
• Botulinum toxin
• Pharmacologic: Calcium channel blockers, Nitrates, Anticholinergics, Beta-adrenergic agonists, Theophylline, Sildenafil
By Dr. Cindy Ye @EmoryGastroHep
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