Refractory Helicobacter Pylori Infection Causes: • Antibiotic resistance (i.e. prior antibiotic exposure to levofloxacin) • Non-adherence (i.e. insufficient acid suppression) • Host genetics (i.e. genes that affect intragastric pH such as CYP2C19) • Non-genetics (i.e. smoking leads to more treatment failure) • H. pylori strain diversity By Dr. Cindy Ye @EmoryGastroHep #Refractory #Helicobacter #Pylori #Infection #HPylori #diagnosis #management #algorithm #gastroenterology
