Satyendra Dhar, MD @DharSaty · 2 years ago
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The Zephyr Endobronchial Valve is an endobronchial implant designed to occlude a hyperinflated lobe of the
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The Zephyr Endobronchial Valve is an endobronchial implant designed to occlude a hyperinflated lobe of the lungs with multiple valves, allowing air to escape while blocking airflow into the treated lobe. This is intended to result in a reduction in lung volume and hyperinflation in the targeted area. This one-way valve therapy leads to an improvement of lung function, exercise tolerance, and quality of life in patients with advanced emphysema.

Key inclusion criteria:
Severe emphysema: forced expiratory volume in 1 second (FEV1) ≤ 45% of predicted, TLC ≥ 100% of predicted, RV ≥ 150% of predicted
Resting partial pressure of arterial carbon dioxide (Paco2) ≤ 60 mm Hg
Resting partial pressure of arterial oxygen (Pao2) on room air ≥ 45 mm Hg
Body mass index ≤ 31 kg/m2 for men, ≤ 32 kg/m2 for women
Abstinence from smoking for at least six months
Completion of pulmonary rehabilitation.

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#copd #emphysema #Zephyr #EndobronchialValve #endobronchialimplant
Satyendra Dhar, MD @DharSaty · 2 years ago
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