Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with no respiratory cause 3) Labs show anion-gap metabolic acidosis 4) Presentation seems like DKA, sepsis, PNA, meningitis 5) History of acute or chronic ingestion/exposure Symptoms: Nausea, Vomiting, Tinnitus, Hearing loss, Dizziness, Altered, Seizure, Coma Exam: Tachypnea, Tachycardia, Elevated temp, Diaphoresis, Pulmonary edema, Shock Labs: Anion-Gap Metabolic Acidosis, Respiratory Alkalosis, High Lactate, Low Potassium, Low Glucose, Salicylate level - Toxic Salicylate Level: 150mg/kg Management: 1) Resuscitation 2) Urine pH > 7.5 with Alkalinzation 3) Glucose > 4.5 mmol/L 4) K > 4.5 mmol/L 5) Dialysis By Sarah Foohey @SarahFoohey #Salicylate #Aspirin #Toxicity #Toxicology #diagnosis #management #Treatment
