1 Thyroglobulin synthesis
Amino acids
Carbohydrates
Peptides
Ribosomes
Capillary
Endoplasmic reticulum
Follicular cell
2 lodine uptake, hormone synthesis, and storage
SCN-
C104
NOZ
Г pool
Nat symport
(NIS)
TSH
Nat
3 Hormone secretion
Primary lysosomes with proteases
Thyroglobulin vesicle
996
Thyroglobulin
Exocytosis
Golgi apparatus
Colloid
Thyroid peroxidase
T3/T4 synthesis
(see Fig. 25.3)
TSH
Т3/T4 storage
(bound to thyroglobulin)
TSH
Endocytosis
T3
Fusion
#Thyroglobulin cleavage
lodotyrosine
dehalogenase
MIT, DIT
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