Lumen
Luminal -
membrane
Nat-K+ ATPase
1
Primary active Nat and K+ transport
Blood
Na
Nat
145
mmol/L
Basolateral membrane
Na
15
mmol/L
2
4[Na*] = Chemical driving force for Nat
Nat
-70 m/
-70 mV
3
Back diffusion of K+
creates membrane potential
-70 mV
4
#Membranepotential
= electrical driving force for Nat
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