Push Dose Pressors - Mixing Instructions. EPINEPHRINE Has alpha and beta 1/2 effects so it is an inopressor Do not give cardiac arrest doses (1 mg) to patients with a pulse Mixing Instructions: • Take a 10 ml syringe with 9 ml of normal saline • Into this syringe, draw up I ml of epinephrine from the cardiac amp (Cardiac amp contains Epinephrine 100 mcg/ml) • Now you have 10 mls of Epinephrine 10 mcg/ml Onset-1 minute Duration-5-10 minutes Dose-0.5-2 ml every 2-5 minutes (5-20 mcg) PHENYLEPHRINE It is pure alpha, so no intrinsic inotropy, and no increase in heart rate, but increases in coronary perfusion can improve cardiac output. Mixing Instructions: • Take a 3 ml syringe and draw up 1 ml of phenylephrine from the vial (vial contains phenylephrine 10 mg/ml) • Inject this into a 100 ml bag of NS • Now you have 100 mls of phenylephrine 100 mcg/ml • Draw up some into a syringe; each ml in the syringe is mcg/ ml Onset-1 minute Duration- 10-20 minutes Dose-0.5-2 ml every 2-5 minutes (50-200 mcg) #Pharmacology #CriticalCare #PushDose #Vasopressors #PDPs #Epinephrine #Phenylephrine #Mixing #Instructions #Recipe