Illustrative example of a patient with acrodermatitis chronica atrophicans. Acrodermatitis chronica atrophicans is a late skin manifestation of Lyme disease that develops insidiously several years after initial infection (range, 0.5–8 years). Approximately 20% of patients have a history of a preceding erythema migrans lesion, usually of the same extremity [242]. Acrodermatitis chronica atrophicans is diagnosed most frequently in women >40 years of age. Although any of the species of Lyme Borrelia may cause the lesion, by far the most common etiologic agent is B. afzelii. #Clinical #Dermatology #Rash #LymeDisease #Acrodermatitis #Chronica #Atrophicans