Core IM: Pearls on Contrast-Induced Nephropathy Definition: • no slam dunk criteria • definition in research studies typically increase in serum creatinine 25-50% within 48-72 hours after contrast exposure Pathogenesis: • no clear explanation • best data from animal models suggests hypoxic/cytotoxic acute tubular necrosis Diagnosis: • look for signs of ATN (muddy brown casts) • FENa (counterintuitive, but sensitivity —100%) #Diagnosis #Management #ContrastInduced #Nephropathy #CIN #PCAKI #Overview
