PROSEVA definition of ARDS Thus, the PROSEVA trial essentially modifies the Berlin definition of ARDS, with the additional requirement that the PaO2/FiO2 ratio remain low despite 12-24 hours of optimization on the ventilator. This improves the specificity of the Berlin definition, because it requires that the PaO2/FiO2 ratio remain stable over time. #Diagnosis #CriticalCare #ARDS #PROSEVA #Definition #PseudoARDS