Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic dysfunction, CSF albumin-cytologic dissociation.
	The sensory and motor systems may be equally affected. 
	The paralysis moves rapidly from lower to upper areas.

Differential diagnosis:
	Myasthenia gravis: Intermittent & worsened by exertion.
	Multiple Sclerosis: CNS demyelination, hyperreflexia, multiple lesions on MRI, oligoclonal bands in CSF.
	Botulism: Descending weakness fixed dilated pupils, food/wound toxin exposure & prominent cranial nerve dysfunction with normal sensation.
	Tick paralysis: Ascending paralysis but spares sensation.
	West Nile virus: Headache, fever, & asymmetric flaccid paralysis but spares sensation.
	Transverse myelitis: Pain, weakness, abnormal sensation, urinary dysfunction, sensory level, hyperreflexia, spinal cord lesion on MRI.
	CIDP: Chronic progression, relapses, requires long-term immunotherapy.
	Spinal Cord Compression: Hyperreflexia, sensory level, MRI shows mass or compression.
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Satyendra Dhar, MD @DharSaty · 1 year ago
Hospital Medicine Clinical Assistant Professor The content and images on this website are provided for educational and informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. The views expressed are those of the authors and do not necessarily reflect those of any affiliated institutions. While efforts are made to ensure accuracy and currency, medical knowledge is continually evolving, and errors or omissions may occur. Users are advised to independently verify information and seek guidance from qualified healthcare professionals for any medical decisions. By using this website, you acknowledge responsibility for your own clinical judgments, and the website and its contributors disclaim any liability arising from the use of its content. 👉 Follow 'Medical Infographics' on 👉 https://www.DharSaty.com
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